Anemia Associated with Chronic Kidney Failure and Its Relationship with Erythropoietin Levels

Abstract

This study examined the relationship between anemia in chronic kidney disease and erythropoietin hormone levels in adult patients in Tripoli, Libya. It aimed to determine the prevalence of this health problem and assess the nature of the relationship between declining kidney function and disruption of the hormone responsible for stimulating red blood cell production. The study adopted a cross-sectional analytical laboratory methodology on a patient sample from Al-Khadra Hospital, measuring a range of hematological indicators including hemoglobin level, erythropoietin hormone, and glomerular filtration rate. Results showed anemia in the majority of patients with a significant decrease in erythropoietin levels proportional to the severity of renal impairment. Accompanying factors such as chronic inflammation also played a role in exacerbating the condition. The study concluded with the importance of developing local

diagnostic and therapeutic protocols focusing on regular erythropoietin measurement and integrated treatment that includes inflammation control and iron deficiency correction alongside hormonal supplementation.